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  • JAMA Internal Medicine June 1, 2016

    Figure: Regression-Adjusted Trends in the Likelihood of a Coding for High Anesthesia Risk by Comorbid Condition From 2005 to 2013

    Probabilities of being coded as being at high risk were predicted by holding patient-level characteristics (procedure type, insurance type, age, sex, service setting, and geographic region) at their means and controlling for comorbid conditions other than the specific condition of interest, including respiratory conditions (sleep apnea, chronic obstructive pulmonary disease [COPD], asthma, and cystic fibrosis), cardiovascular conditions (prior cardiac arrest, congestive heart failure, and coronary artery disease), and other chronic conditions (anemia, cancer, cerebrovascular diseases, dementia, diabetes mellitus, gastrointestinal bleeding, hepatobiliary diseases, human immunodeficiency virus, hypertension, inflammatory bowel disease, pancreatic disease, peripheral artery diseases, psychiatric disorder, renal failure, and other neurological diseases).
  • JAMA Internal Medicine December 1, 2015

    Figure: Unadjusted and Adjusted Effects of Intra-aortic Balloon Pump (IABP) Use on In-Hospital Mortality in Various Situations

    A and B, Intra-aortic balloon pump use was adversely associated with patient outcome, regardless of situation, in crude (A) and multivariable (B) analyses. In the logistic regression model, adjustments were made using all variables exhibiting a bivariate association with the use of IABP with P < .001 in the Table, which included all variables except the following: diabetes mellitus, previous coronary artery bypass graft, chronic lung disease, stable angina or silent ischemia, and 1-vessel disease. C, For evaluating the baseline inequality index, we redefined a list of the following baseline characteristics that are recognized markers of mortality risk: age, cardiogenic shock, prior heart failure, peripheral vascular disease, chronic lung disease, renal dysfunction, NYHA functional classification of at least 3 at the time of percutaneous coronary intervention, and clinical presentation (STEMI or NSTEMI). LMT indicates left main trunk; NSTEMI, non–ST-segment elevation myocardial infarction; NYHA, New York Heart Association; and STEMI, ST-segment elevation myocardial infarction.
  • Metformin Use Reduction in Mild to Moderate Renal Impairment: Possible Inappropriate Curbing of Use Based on Food and Drug Administration Contraindications

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    JAMA Intern Med. 2015; 175(3):458-459. doi: 10.1001/jamainternmed.2014.6936
  • Acute Renal Failure Following Treatment of a Common Culture Contaminant: A Teachable Moment

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    JAMA Intern Med. 2014; 174(12):1890-1891. doi: 10.1001/jamainternmed.2014.5281
  • JAMA Internal Medicine November 1, 2014

    Figure: Summary Estimates of Cardiovascular Outcomes for Revascularization vs Medical Therapy

    A, Mortality incidence was 14.0% for revascularization vs 15.3% for medical therapy (P = .37). B, Hospitalization for heart failure was 9.4% vs 10.4% (P = .40); C, for stroke: 4.1% vs 5.1% (P = .30); and D, for worsening renal function: 15.3% vs 16.1% (P = .67), respectively. ASTRAL indicates Angioplasty and Stenting for Renal Artery Lesions; CORAL, Cardiovascular Outcomes in Renal Atherosclerotic Lesions; DRASTIC, Dutch Renal Artery Stenosis Intervention Cooperative; EMMA, Essai Multicentrique Medicaments vs Angioplastie; NITER, Nephropathy Ischemic ThERapy; RASCAD, Renal Artery Stenosis in Coronary Artery Disease; RR, risk ratio; SNARSCG, Scottish and Newcastle Renal Artery Stenosis Collaborative Group; STAR, STent placement and blood pressure and lipid-lowering for the prevention of progression of renal dysfunction caused by Atherosclerotic ostial stenosis of the Renal artery.
  • A Risk Prediction Score for Kidney Failure or Mortality in Rhabdomyolysis

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    JAMA Intern Med. 2013; 173(19):1821-1827. doi: 10.1001/jamainternmed.2013.9774

    McMahon et al develop a risk prediction tool to identify patients at greatest risk of renal replacement therapy or in-hospital mortality. See the invited critique by Wilhelm-Leen and Winkelmayer.

  • Predicting the Outcomes of Rhabdomyolysis: A Good Starting Point

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    JAMA Intern Med. 2013; 173(19):1828-1829. doi: 10.1001/jamainternmed.2013.9235
  • Elmo's Story

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    Arch Intern Med. 2012; 172(2):185-185. doi: 10.1001/archinternmed.2011.793
  • ALLHAT Findings Revisited in the Context of Subsequent Analyses, Other Trials, and Meta-analyses—Reply

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    Arch Intern Med. 2009; 169(19):1806-1818. doi: 10.1001/archinternmed.2009.372
  • Editor's Correspondence: COMMENTS AND OPINIONS

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    Arch Intern Med. 2009; 169(8):809-813. doi: 10.1001/archinternmed.2009.81
  • RAAS Blockade, Renal Failure, ESRD, and Death Among African Americans in the AASK Posttrial Cohort Study

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    Arch Intern Med. 2008; 168(21):2383-2384. doi: 10.1001/archinternmed.2008.510
  • Prophylaxis Against Deep Vein Thrombosis in Critically Ill Patients With Severe Renal Insufficiency With the Low-Molecular-Weight Heparin Dalteparin: An Assessment of Safety and Pharmacodynamics: The DIRECT Study

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    Arch Intern Med. 2008; 168(16):1805-1812. doi: 10.1001/archinte.168.16.1805
  • A Prognostic Risk Index for Long-term Mortality in Patients With Peripheral Arterial Disease

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    Arch Intern Med. 2007; 167(22):2482-2489. doi: 10.1001/archinte.167.22.2482
  • JAMA Internal Medicine October 9, 2006

    Figure: Annual Influenza Vaccination in Community-Dwelling Elderly Individuals and the Risk of Lower Respiratory Tract Infections or Pneumonia

    Association between the first influenza vaccination (1st vac) or revaccination (revac) and lower respiratory tract infection during influenza epidemic periods, stratified by year. Adjustment has been made for sex, underlying chronic diseases (cardiovascular and respiratory diseases; neurological and psychiatric disorders; hypertension; malignancies; renal insufficiency; and diabetes mellitus), smoking, number of antibiotic prescriptions, and number of visits to a general practitioner. On the x-axis, the first vaccination, any revaccination, and revaccination vs first vaccination are all fully adjusted. On the y-axis, the hazard ratio (HR) indicates the risk of lower respiratory tract infection following first vaccination or revaccination vs no vaccination, or following revaccination vs first vaccination. Error bars indicate 95% confidence intervals (CIs).
  • JAMA Internal Medicine September 25, 2006

    Figure: Erythropoietin Resistance During Androgen Deficiency

    Median erythropoietin and total testosterone levels in men without polycystic renal disease receiving chronic dialysis for renal failure. To convert testosterone to nanomoles per liter, multiply by 0.0347.
  • The Dogma of “Tight Control”: Beyond the Limits of Evidence

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    Arch Intern Med. 2006; 166(15):1671-1672. doi: 10.1001/archinte.166.15.1671-b
  • JAMA Internal Medicine April 24, 2006

    Figure 4: Depressive Symptoms After Acute Myocardial Infarction: Evidence for Highest Rates in Younger Women

    Odds ratio (95% confidence intervals) plot for multivariable logistic regression modeling Primary Care Evaluation of Mental Disorders Brief Patient Health Questionnaire depression score of 10 or higher. Age-sex effect controlling for site, demographic factors (race, marital status, and level of education), patients' perceived economic burden, history of smoking, medical history (diabetes, hypertension, hypercholesterolemia, cerebrovascular accidents, angina, myocardial infarction, coronary artery bypass grafting, percutaneous coronary intervention, peripheral vascular disease, lung disease), and clinical status on admission (congestive heart failure, systolic blood pressure, renal failure).
  • JAMA Internal Medicine May 9, 2005

    Figure: Alcohol Consumption and the Risk of Renal Dysfunction in Apparently Healthy Men

    Multivariable-adjusted odds ratios for renal dysfunction (creatinine level ≥1.5 mg/dL [≥133 μmol/L]) according to alcohol consumption categories. P = .008 for trend. Error bars indicate 95% confidence intervals.
  • Alcohol Consumption and the Risk of Renal Dysfunction in Apparently Healthy Men

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    Arch Intern Med. 2005; 165(9):1048-1053. doi: 10.1001/archinte.165.9.1048
  • Concealed Renal Insufficiency and Adverse Drug Reactions in Elderly Hospitalized Patients

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    Arch Intern Med. 2005; 165(7):790-795. doi: 10.1001/archinte.165.7.790