http://archinte.jamanetwork.com/ en-us Wed, 19 Dec 2012 00:00:00 GMT Tue, 01 Jan 2013 00:48:18 GMT Silverchair editor@archinte.jamanetwork.com webmaster@archinte.jamanetwork.com http://archinte.jamanetwork.com/article.aspx?articleID=1108645 Mon, 23 Jan 2012 00:00:00 GMT Simonelli S, Gianazza E, Mombelli G, et al. <span class="paragraphSection">An antibody against the lecithin:cholesterol acyltransferase (LCAT) enzyme, which negates cholesterol esterification in plasma, causing severe high-density lipoprotein deficiency (HD), was identified in a woman with a large-cell non-Hodgkin lymphoma. Successful treatment of the lymphoma resulted in clearance of the antibody and complete correction of the defective cholesterol esterification and HD. To our knowledge, an acquired LCAT deficiency leading to severe HD has not been reported previously in association with a malignant disease, and this patient represents the first such documented case.</span> 172 2 179 181 10.1001/archinternmed.2011.661 http://archinte.jamanetwork.com/article.aspx?articleID=1108645