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 Showing 81-95 of 95 Articles
Invited Commentary 
Margaret E. Wierman, MD

There is a developing story that the increased use of testosterone therapy without a diagnosis of hypogonadism is associated with an elevated cardiovascular risk for some patients. In this issue of JAMA Internal Medicine, Layton and coauthors1 deepen our knowledge with their analysis of 3 large ...

Invited Commentary 
Scott M. Stevens, MD; Scott C. Woller, MD

Venous thromboembolism, which most commonly manifests as deep venous thrombosis (DVT) of the extremities and pulmonary embolism, affects more than 500 000 Americans annually and is the third most common cause of cardiovascular mortality in the United States. Upper-extremity DVT (UE-DVT) accounts for about 10% of all DVT ...

Editor's Note 
Joseph S. Ross, MD, MHS; Rita F. Redberg, MD, MSc

The competing concerns and interests of both individuals and society must be considered when establishing regulatory policy. In 2008, the US Food and Drug Administration (FDA) banned albuterol inhalers containing chlorofluorocarbons. This decision was questioned at the time because the chlorofluorocarbons emitted from inhalers have an insignificant effect ...

Research Letter 
Michelangelo Sartori, MD, PhD; Ludovica Migliaccio, BSc; Elisabetta Favaretto, MD; Carlotta Brusi, MD; Eleonora Conti, MD; Giuseppina Rodorigo, MD; Benilde Cosmi, MD, PhD

Upper-extremity deep venous thrombosis (UE-DVT) accounts for approximately 14% of all cases of DVT.1 Because UE-DVT may provoke pulmonary embolism (PE), prompt diagnosis is necessary to select the patients who require anticoagulation. This study aimed to evaluate the failure rate of ultrasonographic screening for UE-DVT.

Invited Commentary: Whole-Arm Ultrasound for Upper-Extremity Deep Venous Thrombosis; Scott M. Stevens, MD; Scott C. Woller, MD
Viewpoint 
Katherine Baicker, PhD; Amitabh Chandra, PhD

This Viewpoint explains how cost sharing in employer-sponsored health insurance plans affects low- and high-wage workers differently and advocates regulatory changes that would both improve health and control costs.

Teachable Moment 
Spyridoula Maraka, MD; Derek T. O’Keeffe, MBBChBAO; Victor M. Montori, MD
Teachable Moment 
Linh T. Nguyen, BS; Christopher T. Sullivan, BA; Anil N. Makam, MD, MAS
Original Investigation 
Saurav Chatterjee, MD; Howard C. Herrmann, MD; Robert L. Wilensky, MD; John Hirshfeld, MD; Daniel McCormick, DO; David S. Frankel, MD; Robert W. Yeh, MD, MSc; Ehrin J. Armstrong, MD; Dharam J. Kumbhani, MD, SM, MRCP; Jay Giri, MD, MPH

Importance  The Lariat device has received US Food and Drug Administration (FDA) 510(k) clearance for soft-tissue approximation and is being widely used off-label for left atrial appendage (LAA) exclusion. A comprehensive analysis of safety and effectiveness has not been reported.

Objectives  To perform a systematic review ...

Invited Commentary: Lariat—Small Step or Giant Leap?; Paul D. Varosy, MD
Invited Commentary 
Paul D. Varosy, MD
Editor's Note 
Deborah Grady, MD, MPH

This Editorial Note discusses an intervention to reduce inappropriate use of central venous catheters in hospitalized patients.

Challenges in Clinical Electrocardiography 
Kevin K. Manocha, MD; David Snipelisky, MD; Nandan S. Anavekar, MD

A woman in her 70s with a medical history significant for atrial fibrillation and cardioembolic stroke who was receiving long-term anticoagulation therapy with warfarin (international normalized ratio, 2.3) presented to an outside facility with sudden onset of nausea and vertigo. Her mental status declined and she was unable ...

Research Letter 
Emily G. McDonald, MD; Todd C. Lee, MD, MPH

Central venous catheters (CVCs) facilitate secure access in critically ill patients and allow for the administration of caustic substances. Potential harms include bloodstream infections1 and thromboembolism.2 A recent study showed that 21.2% of physicians were unaware that their patient had a CVC3 and therefore were ...

Editor's Note: Reducing Inappropriate Use of Central Venous Catheters; Deborah Grady, MD, MPH
Perspective 
Saurabh Jha, MD, MS

“She had a normal CT yesterday. Why another?” I asked the physician.

Teachable Moment 
Wade Nicholson Harrison, MPH; John F. Dick III, MD; Thom Walsh, PhD
Research Letter 
Adam Bonica, PhD; Howard Rosenthal, PhD; David J. Rothman, PhD

We recently reported that between 1991 and 2012, the political alignment of American physicians shifted from predominantly Republican toward the Democrats.1 In 2014, the Republican surge changed party control of Congress: the Republicans gained 9 Senate seats and became the majority party there, and the Republican majority ...

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