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Invited Commentary 
Michael K. Ong, MD, PhD

Tobacco use continues to be the leading preventable cause of mortality in the United States, despite a decrease in the overall prevalence of cigarette smoking. In this issue of JAMA Internal Medicine, Siegel et al1 report that cigarette smoking continues to be the attributable cause of ...

Research Letter 
Rebecca L. Siegel, MPH; Eric J. Jacobs, PhD; Christina C. Newton, MSPH; Diane Feskanich, ScD; Neal D. Freedman, PhD; Ross L. Prentice, PhD; Ahmedin Jemal, DVM, PhD

This study estimated the number of deaths attributable to cigarette smoking for 12 smoking-related cancers and found that continued progress in reducing cancer mortality requires more comprehensive tobacco control.

Invited Commentary: Tobacco Cessation; Michael K. Ong, MD, PhD
Original Investigation 
Kelvin K. F. Tsoi, PhD; Joyce Y. C. Chan, MPH; Hoyee W. Hirai, MSc; Samuel Y. S. Wong, MD; Timothy C. Y. Kwok, MD, PhD
Includes: Supplemental Content

Importance  Dementia is a global public health problem. The Mini-Mental State Examination (MMSE) is a proprietary instrument for detecting dementia, but many other tests are also available.

Objective  To evaluate the diagnostic performance of all cognitive tests for the detection of dementia.

Data Sources  Literature ...

Invited Commentary: Copyright in Cognitive Testing; John C. Newman, MD, PhD
Research Letter 
Michael T. M. Wang; Mark J. Bolland, MBChB, PhD; Andrew Grey, MD

Observational research is abundant and influences clinical practice, in part via publication in high-impact journals and dissemination by news media. However, it frequently generates unreliable findings.1 Inherent methodologic limitations that generate bias and confounding mean that causal inferences cannot reliably be drawn. Study limitations may be inadequately ...

Editor's Note 
Rachel J. Stern, MD; Blake Charlton, MD

Today, a small but significant amount of our education as house officers comes from pop-up alerts in the electronic medical record (EMR). Medical school lectures shaped our understanding of venous thromboembolism prophylaxis, antibiotic stewardship, and transfusion of blood products. In residency, EMR-based clinical decision support (CDS) tools cement ...

Research Letter 
Elliot B. Tapper, MD; Neil Sengupta, MD; Michelle Lai, MD, MPH; Gary Horowitz, MD, PhD

This before-and-after comparison study reports that physician ordering patterns of ceruloplasmin tests decreased after a decision pop-up tool was added to the electronic medical record system at Beth Israel Deaconess Medical Center.

Editor's Note: Maximizing EMRs; Rachel J. Stern, MD; Blake Charlton, MD
Comment & Response 
Charlotte Andersson, MD, PhD

To the Editor We have regretfully discovered an error in our program underlying the analyses of the paper “Association of β-Blocker Therapy With Risks of Adverse Cardiovascular Events and Deaths in Patients With Ischemic Heart Disease Undergoing Noncardiac Surgery: A Danish Nationwide Cohort Study” (2014;174[3]:336-344).1

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