We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......

Basic View | Expanded View
 Showing 41-60 of 95 Articles
Research Letter 
Michael T. M. Wang; Mark J. Bolland, MBChB, PhD; Andrew Grey, MD

Observational research is abundant and influences clinical practice, in part via publication in high-impact journals and dissemination by news media. However, it frequently generates unreliable findings.1 Inherent methodologic limitations that generate bias and confounding mean that causal inferences cannot reliably be drawn. Study limitations may be inadequately ...

Original Investigation 
Mark W. Friedberg, MD, MPP; Meredith B. Rosenthal, PhD; Rachel M. Werner, MD, PhD; Kevin G. Volpp, MD, PhD; Eric C. Schneider, MD, MSc
Includes: Supplemental Content

Importance  Published evaluations of medical home interventions have found limited effects on quality and utilization of care.

Objective  To measure associations between participation in the Northeastern Pennsylvania Chronic Care Initiative and changes in quality and utilization of care.

Design, Setting, and Participants  The northeast region ...

Invited Commentary: Assessing Effectiveness of the Patient-Centered Medical Home; George L. Jackson, PhD, MHA; John W. Williams Jr, MD, MHS
Original Investigation 
Marie Marklund, PhD, DDS; Bo Carlberg, MD, PhD; Lars Forsgren, MD, PhD; Tommy Olsson, MD, PhD; Hans Stenlund, PhD; Karl A. Franklin, MD, PhD
Includes: Supplemental Content

Importance  Oral appliances that move the mandible forward during sleep are suggested as treatment for mild to moderate obstructive sleep apnea.

Objective  To test whether an adjustable, custom-made oral appliance improves daytime sleepiness and quality of life in patients with daytime sleepiness and snoring or mild ...

Invited Commentary: Mandibular Advancement Therapy for Obstructive Sleep Apnea; Winfried J. Randerath, MD
Original Investigation 
Paula Chatterjee, MD, MPH; Atheendar S. Venkataramani, MD, PhD; Anitha Vijayan, MD; Jason R. Wellen, MD, MBA; Erika G. Martin, PhD, MPH
Includes: Supplemental Content

Importance  Shortages in transplantable solid organs remain a critical public health challenge in the United States. During the past 2 decades, all states have implemented policies to increase organ supply, although their effectiveness is unknown.

Objective  To determine the effects on organ donation and transplantation rates ...

Invited Commentary: Testing Incentives to Increase Organ Donation; Sally Satel, MD; David C. Cronin II, MD, PhD, MHCM
Invited Commentary 
Winfried J. Randerath, MD

Obstructive sleep apnea (OSA) is a major medical challenge: it affects 4% to 13% of the general population, impairs quality of life, and substantially increases the risk of motor vehicle accidents. Obstructive sleep apnea is associated with cardiovascular and metabolic consequences and increased mortality, particularly among the most ...

Invited Commentary 
George L. Jackson, PhD, MHA; John W. Williams Jr, MD, MHS

Much as clinical research has the goal of helping clinicians improve their decision making for individual patients, health services research has the ultimate goal of helping managers and policy makers make better decisions for their organizations and constituents. Many managers of third-party-payer and provider organizations want to know ...

Invited Commentary 
Sally Satel, MD; David C. Cronin II, MD, PhD, MHCM

This Invited Commentary discusses the effectiveness of state policies to encourage organ donation and transplantation in the United States.

Editor's Note 
Rachel J. Stern, MD; Blake Charlton, MD

Today, a small but significant amount of our education as house officers comes from pop-up alerts in the electronic medical record (EMR). Medical school lectures shaped our understanding of venous thromboembolism prophylaxis, antibiotic stewardship, and transfusion of blood products. In residency, EMR-based clinical decision support (CDS) tools cement ...

Special Communication  FREE
Lynne Warner Stevenson, MD

The number of heart transplants performed in the United States was 2177 in 1994 and 2166 in 2014. However, the number of transplant centers has increased, and the criteria for transplants have broadened to include patients 65 years or older, those with a body mass index greater than ...

Research Letter 
Elliot B. Tapper, MD; Neil Sengupta, MD; Michelle Lai, MD, MPH; Gary Horowitz, MD, PhD

This before-and-after comparison study reports that physician ordering patterns of ceruloplasmin tests decreased after a decision pop-up tool was added to the electronic medical record system at Beth Israel Deaconess Medical Center.

Editor's Note: Maximizing EMRs; Rachel J. Stern, MD; Blake Charlton, MD
Comment & Response 
Charlotte Andersson, MD, PhD

To the Editor We have regretfully discovered an error in our program underlying the analyses of the paper “Association of β-Blocker Therapy With Risks of Adverse Cardiovascular Events and Deaths in Patients With Ischemic Heart Disease Undergoing Noncardiac Surgery: A Danish Nationwide Cohort Study” (2014;174[3]:336-344).1

Original Investigation 
Katherine A. Ornstein, PhD, MPH; Melissa D. Aldridge, PhD, MPH, MBA; Melissa M. Garrido, PhD; Rebecca Gorges, MS; Diane E. Meier, MD; Amy S. Kelley, MD, MS
Includes: Supplemental Content

Importance  Family caregivers of individuals with serious illness are at risk for depressive symptoms and depression. Hospice includes the provision of support services for family caregivers, yet evidence is limited regarding the effect of hospice use on depressive symptoms among surviving caregivers.

Objective  To determine the ...

Invited Commentary: The Antidepressant Effect of Hospice; Holly G. Prigerson, PhD; Kelly Trevino, PhD
Original Investigation 
Nathan P. Clark, PharmD; Daniel M. Witt, PharmD; Loren E. Davies, PharmD; Edward M. Saito, PharmD; Kathleen H. McCool, PharmD; James D. Douketis, MD; Kelli R. Metz, PharmD; Thomas Delate, PhD

Importance  The risk of bleeding and recurrent venous thromboembolism (VTE) among patients receiving long-term warfarin sodium therapy for secondary VTE prevention who require temporary interruption of anticoagulant therapy for surgery or invasive diagnostic procedures has not been adequately described.

Objective  To describe the rates of clinically ...

Invited Commentary: Overuse of Bridging Anticoagulation for Patients With VTE; Daniel J. Brotman, MD; Michael B. Streiff
Original Investigation 
Katherine A. Ornstein, PhD, MPH; Bruce Leff, MD; Kenneth E. Covinsky, MD; Christine S. Ritchie, MD, MSPH; Alex D. Federman, MD, MPH; Laken Roberts, MPH; Amy S. Kelley, MD, MSHS; Albert L. Siu, MD, MSPH; Sarah L. Szanton, PhD

Importance  Increasing numbers of older, community-dwelling adults have functional impairments that prevent them from leaving their homes. It is uncertain how many people who live in the United States are homebound.

Objectives  To develop measures of the frequency of leaving and ability to leave the home ...

Original Investigation 
Barbara W. Trautner, MD, PhD; Larissa Grigoryan, MD, PhD; Nancy J. Petersen, PhD; Sylvia Hysong, PhD; Jose Cadena, MD; Jan E. Patterson, MD, MS; Aanand D. Naik, MD
Includes: Supplemental Content

Importance  Overtreatment of asymptomatic bacteriuria (ASB) in patients with urinary catheters remains high. Health care professionals have difficulty differentiating cases of ASB from catheter-associated urinary tract infections.

Objectives  To evaluate the effectiveness and sustainability of an intervention to reduce urine culture ordering and antimicrobial prescribing for ...

Invited Commentary: Changing Clinicians’ Behavior; Manisha Juthani-Mehta, MD
Invited Commentary 
Holly G. Prigerson, PhD; Kelly Trevino, PhD

Although caring for a terminally ill spouse can be gratifying, it can also be depressing. Research1,2 has shown that caregiving poses risks to a spouse’s mental health both before and after the ill spouse dies. Depending on the circumstances of the death, psychological distress may ...

Invited Commentary 
Daniel J. Brotman, MD; Michael B. Streiff

Patients receiving anticoagulation for venous thromboembolism (VTE) have varying risks of recurrence on cessation of the therapy. Time from the most recent thrombotic event is perhaps the most important determinant of short-term VTE recurrence because patients who stop anticoagulation therapy before the stabilization of an active thrombus are ...

Invited Commentary 
Manisha Juthani-Mehta, MD

Asymptomatic bacteriuria (ASB) is one of the most common reasons for inappropriate antimicrobial use.1 Despite the recommendation for decades that patients with indwelling urinary catheters should not be screened for ASB or treated with antimicrobial therapy, this practice is still commonplace.2 In an effort to have ...

Invited Commentary 
Ralph G. Brindis, MD, MPH; M. Eugene Sherman, MD

With the need and desire for Congress and the Centers for Medicare & Medicaid Services (CMS) to reduce the nation’s unsustainable financial burden of Medicare, substantial reduction in payments of many imaging tests and procedures has been implemented for in-office provision of these services. Imaging was chosen because ...

Research Letter 
Theora Cimino, BS; Michael A. Steinman, MD; Susan L. Mitchell, MD, MPH; Yinghui Miao, MPH; Monica Bharel, MD, MPH; Caroline E. Barnhart, BA; Rebecca T. Brown, MD, MPH

This observational study suggests monitoring of older homeless adults to identify appropriate services.

Sign in

Purchase Options

• Subscribe to the journal
• Rent this article ?

A free personal account provides

• Free current issues on The JAMA Network Reader
• Free quizzes on The JAMA Network Challenge
• Commenting and personalized alerts