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Basic View | Expanded View
 Showing 41-60 of 68 Articles
Teachable Moment 
Hina N. Mehta, MD; Xue Chi; Fred R. Buckhold, MD

In this case, a patient was exposed to several potential harms to prevent consequences of a low-risk procedure.

Original Investigation 
Eric G. Campbell, PhD; Christine Vogeli, PhD; Sowmya R. Rao, PhD; Melissa Abraham, PhD; Roz Pierson, PhD; Sandra Applebaum, MA
Includes: Supplemental Content

Importance  For the past decade, more attention and concern has been directed toward financial relationships between the life science industry and physicians. Relationships between industry and institutional review board (IRB) members represent an important subclass that has the potential to broadly influence decisions regarding medical research.


Invited Commentary: Advancing Science in the Service of Humanity; Laura Weiss Roberts, MD, MA
Original Investigation 
Walter Ageno, MD; Nicoletta Riva, MD; Sam Schulman, MD; Jan Beyer-Westendorf, MD; Soo Mee Bang, MD; Marco Senzolo, MD; Elvira Grandone, MD; Samantha Pasca, MD; Matteo Nicola Dario Di Minno, MD; Rita Duce, MD; Alessandra Malato, MD; Rita Santoro, MD; Daniela Poli, MD; Peter Verhamme, MD; Ida Martinelli, MD; Pieter Kamphuisen, MD; Doyeun Oh, MD; Elbio D’Amico, MD; Cecilia Becattini, MD; Valerio De Stefano, MD; Gianpaolo Vidili, MD; Antonella Vaccarino, MD; Barbara Nardo, MD; Marcello Di Nisio, MD; Francesco Dentali, MD
Includes: Supplemental Content

Importance  Little information is available on the long-term clinical outcome of patients with splanchnic vein thrombosis (SVT).

Objective  To assess the incidence rates of bleeding, thrombotic events, and mortality in a large international cohort of patients with SVT.

Design, Setting, and Participants  A prospective cohort ...

Invited Commentary 
Laura Weiss Roberts, MD, MA

Is human experimentation ever ethically permissible? Are human studies always and inevitably exploitative? Since the release of the Belmont Report1 in the United States in 1979, the response to these difficult ethical questions has been that people may participate in scientific studies when the following 2 conditions ...

Invited Commentary 
Jack Ansell, MD

The commentary discusses the implications of the study on anticoagulant therapy for splanchnic vein thrombosis from the International Society on Thrombosis and Hemostasis registry.

Evidence to Practice 
Jeffrey A. Tice, MD; Harinder S. Chahal, PharmD, MSc; Daniel A. Ollendorf, PhD

This evidence report on interferon-free therapy for chronic hepatitis C virus infection includes a systematic review of the literature, a cost-effectiveness model, and a budget impact assessment to support a December 2014 public meeting of the California Technology Assessment Forum.

This Viewpoint considers that breast density notification laws are unlikely to improve our understanding of breast cancer risk, screening, and diagnosis or to save lives and instead may result in substantial personal harms and societal costs.

Invited Commentary: Effect of Screening Mammography on Cancer Incidence and Mortality; Joann G. Elmore, MD, MPH; Ruth Etzioni, PhD
Original Investigation 
Bradley H. Crotty, MD, MPH; Jan Walker, RN, MBA; Meghan Dierks, MD; Lewis Lipsitz, MD; Jacqueline O’Brien, BS; Shira Fischer, MD, PhD; Warner V. Slack, MD; Charles Safran, MD, MS
Includes: Supplemental Content

Importance  Elderly patients often share control of their personal health information and decision making with family and friends when needed. Patient portals can help with information sharing, but concerns about privacy and autonomy of elderly patients remain. Health systems that implement patient portals would benefit from guidance ...

Invited Commentary: Information Sharing Preferences of Older Patients and Their Families; Pravene A. Nath, MD, MSE; Christopher D. Sharp, MD
Original Investigation 
Jade Q. Wu, MA; Erica R. Appleman, MA; Robert D. Salazar, MA; Jason C. Ong, PhD
Includes: Supplemental Content

Importance  Cognitive behavioral therapy for insomnia (CBT-I) is the most prominent nonpharmacologic treatment for insomnia disorders. Although meta-analyses have examined primary insomnia, less is known about the comparative efficacy of CBT-I on comorbid insomnia.

Objective  To examine the efficacy of CBT-I for insomnia comorbid with psychiatric ...

Invited Commentary: Treating Insomnia With Medical and Psychiatric Comorbidities; Michael A. Grandner, PhD, MTR; Michael L. Perlis, PhD
Original Investigation 
Charles Harding, AB; Francesco Pompei, PhD; Dmitriy Burmistrov, PhD; H. Gilbert Welch, MD, MPH; Rediet Abebe, MASt; Richard Wilson, DPhil
Includes: Supplemental Content

Importance  Screening mammography rates vary considerably by location in the United States, providing a natural opportunity to investigate the associations of screening with breast cancer incidence and mortality, which are subjects of debate.

Objective  To examine the associations between rates of modern screening mammography and the ...

Invited Commentary: Effect of Screening Mammography on Cancer Incidence and Mortality; Joann G. Elmore, MD, MPH; Ruth Etzioni, PhD
Invited Commentary 
Pravene A. Nath, MD, MSE; Christopher D. Sharp, MD

The development of technology that drives and enables engagement with patients and their families is accelerating at an unprecedented pace. Demand is driven by patients seeking the best quality and experience as well as by health care organizations, payers, and policy makers in response to health care costs, ...

Invited Commentary 
Michael A. Grandner, PhD, MTR; Michael L. Perlis, PhD

Insomnia is a common condition. It is estimated that approximately 30% of the population experiences some symptom of insomnia, and approximately 5% to 15% of these individuals are likely to meet criteria for an insomnia disorder.1 Traditionally, insomnia was considered as either a primary disorder or secondary ...

Invited Commentary 
Joann G. Elmore, MD, MPH; Ruth Etzioni, PhD

With increasing availability of massive quantities of health care data and advances in technology for data analyses, novel investigations of health delivery and outcomes are proliferating. In this issue of JAMA Internal Medicine, Harding et al1 investigate the health effects of screening mammography through the merging ...

Research Letter 
Matthew J. Maurice, MD; Robert Abouassaly, MD, MS; Simon P. Kim, MD, MPH; Hui Zhu, MD, ScD

This study examined the use of active surveillance and its predictors in prostate cancer treatment, finding that its use is low and should increase to reduce the overtreatment of screening-detected prostate cancer.

Renu Mansukhani, MD

As I sat down for my visit with dad, I turned on my cell phone’s voice recorder. He did not notice. I did not want him to know that I was doing it because I did not want him to realize that I was starting to treat every ...

Original Investigation 
Elizabeth A. Regan, MD; David A. Lynch, MD; Douglas Curran-Everett, PhD; Jeffrey L. Curtis, MD; John H. M. Austin, MD; Philippe A. Grenier, MD; Hans-Ulrich Kauczor, MD; William C. Bailey, MD; Dawn L. DeMeo, MD; Richard H. Casaburi, PhD, MD; Paul Friedman, MD; Edwin J. R. Van Beek, MD; John E. Hokanson, PhD; Russell P. Bowler, MD; Terri H. Beaty, PhD; George R. Washko, MD; MeiLan K. Han, MD; Victor Kim, MD; Song Soo Kim, MD; Kunihiro Yagihashi, MD; Lacey Washington, MD; Charlene E. McEvoy, MD; Clint Tanner, MD; David M. Mannino, MD; Barry J. Make, MD; Edwin K. Silverman, MD; James D. Crapo, MD; for the Genetic Epidemiology of COPD (COPDGene) Investigators
Includes: Supplemental Content

Importance  Airflow obstruction on spirometry is universally used to define chronic obstructive pulmonary disease (COPD), and current or former smokers without airflow obstruction may assume that they are disease free.

Objective  To identify clinical and radiologic evidence of smoking-related disease in a cohort of current and ...

Research Letter 
Kush R. Desai, MD; Robert J. Lewandowski, MD; Riad Salem, MD, MBA; Samdeep K. Mouli, MD; Jennifer K. Karp, RN; James L. Laws, BS; Robert K. Ryu, MD

This single-center review reports that retrieval of inferior vena cava filters after a prolonged dwell time has a high rate of safety and success in patients at risk for pulmonary embolism.

Teachable Moment 
Sarah M. Kuhn, MD; Ruchi Jain, DO; Kristi M. Moore, MD
Teachable Moment 
Michael J. Nabozny, MD; Nicole M. Steffens, MPH; Margaret L. Schwarze, MD, MPP
Original Investigation 
Elyse R. Park, PhD, MPH; Ilana F. Gareen, PhD; Sandra Japuntich, PhD; Inga Lennes, MD; Kelly Hyland, BA; Sarah DeMello, MS; JoRean D. Sicks, MS; Nancy A. Rigotti, MD
Includes: Supplemental Content

Importance  The National Lung Screening Trial (NLST) found a reduction in lung cancer mortality among participants screened with low-dose computed tomography vs chest radiography. In February 2015, Medicare announced its decision to cover annual lung screening for patients with a significant smoking history. These guidelines promote smoking ...

Invited Commentary: Tobacco Cessation; Michael K. Ong, MD, PhD

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