We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......

Basic View | Expanded View
 Showing 21-40 of 76 Articles
Research Letter 
Penny Yin, MD; Alex Kiss, PhD; Jerome A. Leis, MD, MSc

This cohort study of appropriate orders for urinalysis determines whether overuse of urinalysis contributes to misdiagnosis and excessive use of antibiotics among elderly patients admitted to the emergency department of a tertiary care center.

Original Investigation  FREE
Marianne C. Snijdewind, MA; Dick L. Willems, MD, PhD; Luc Deliens, PhD; Bregje D. Onwuteaka-Philipsen, PhD; Kenneth Chambaere, PhD

Importance  Right to Die NL, an organization in the Netherlands that advocates for the option of euthanasia, founded the End-of-Life Clinic in 2012 to provide euthanasia or physician-assisted suicide for patients who meet all legal requirements but whose regular physicians rejected their request. Many patients whose requests ...

Invited Commentary: Euthanasia in Belgium and the Netherlands; Barron H. Lerner, MD, PhD; Arthur L. Caplan, PhD
Invited Commentary 
Muriel R. Gillick, MD

Facing death is rarely easy. As dying becomes an imminent reality rather than a remote inevitability, patients often have difficulty choosing among treatment alternatives, even if they are cognitively intact. Health care proxies, when confronting options ranging from burdensome, invasive treatment to exclusively palliative care, frequently are uncertain ...

Invited Commentary  FREE
Barron H. Lerner, MD, PhD; Arthur L. Caplan, PhD

The slippery slope is an argument frequently invoked in the world of bioethics. It connotes the notion that a particular course of action will lead inevitably to undesirable and unintended consequences. Saying no to the original action, even if that act is moral in itself, may, in light ...

Special Communication 
Andrew B. Cohen, MD, DPhil; Megan S. Wright, PhD; Leo Cooney Jr, MD; Terri Fried, MD
Includes: Supplemental Content

As the population ages, more adults will develop impaired decision-making capacity and have no family members or friends available to make medical decisions on their behalf. In such situations, a professional guardian is often appointed by the court. This official has no preexisting relationship with the impaired individual ...

Invited Commentary: Guidance in Shared Decision Making; Muriel R. Gillick, MD
Research Letter 
Sigrid Dierickx, MSc; Luc Deliens, PhD; Joachim Cohen, PhD; Kenneth Chambaere, PhD

This study examined the shifts in the expression and granting of euthanasia requests between 2007 and 2013 and the reasons that physicians granted or denied these requests.

Invited Commentary: Euthanasia in Belgium and the Netherlands; Barron H. Lerner, MD, PhD; Arthur L. Caplan, PhD
Research Letter 
Erika H. Newton, MD, MPH; Erin A. Zazzera, RN, MPH; Guillaume Van Moorsel, MPH, MLIS; Brenda E. Sirovich, MD, MS

This data analysis identified outpatient and emergency department process measures to determine to what extent the measures preferentially target underuse vs overuse.

Teachable Moment 
Anne-Laure Sennesael, MSc; Jean-Michel Dogné, PhD; Anne Spinewine, PhD

While direct oral anticoagulants (DOACs) hold some advantages over vitamin K antagonists, DOAC adverse effects, including bleeding, present a clinical challenge in frail older patients.

Original Investigation 
Karen E. Hansen, MD, MS; R. Erin Johnson, BS; Kaitlin R. Chambers, BS; Michael G. Johnson, MS; Christina C. Lemon, MS, RD, CD; Tien Nguyen Thuy Vo, MS; Sheeva Marvdashti, BS
Includes: Supplemental Content

Importance  Experts debate optimal 25-hydroxyvitamin D (25[OH]D) levels for musculoskeletal health.

Objective  To compare the effects of placebo, low-dose cholecalciferol, and high-dose cholecalciferol on 1-year changes in total fractional calcium absorption, bone mineral density, Timed Up and Go and five sit-to-stand tests, and muscle mass in ...

Editor's Note: How Much Vitamin D Is Enough?; Deborah Grady, MD, MPH
Invited Commentary 
Donna M. Polk, MD, MPH; Patrick T. O’Gara, MD

Comprehensive, multidisciplinary cardiac rehabilitation programs reduce cardiovascular morbidity and mortality. They also improve exercise capacity, atherosclerotic risk markers, quality of life (QOL), and patient adherence to medication and lifestyle recommendations. They are best viewed as aggressive programs of secondary prevention. The multifaceted interventions these programs offer include exercise ...

Editor's Note 
Deborah Grady, MD, MPH

There is ongoing controversy regarding the definition of vitamin D insufficiency and the optimal treatment goal: should treatment aim to maintain a serum vitamin D level above 20 ng/mL or above 30 ng/mL? We found the randomized clinical trial by Hansen et al1 informative because it enrolled ...

Challenges in Clinical Electrocardiography 
Jordan C. Ray, MD; Fred Kusumoto, MD; Nora Goldschlager, MD

Test your knowledge with an electrocardiogram quiz case involving P-wave mimicry.

Research Letter 
Jacob A. Doll, MD; Anne Hellkamp, MS; P. Michael Ho, MD, PhD; Michael C. Kontos, MD; Mary A. Whooley, MD; Eric D. Peterson, MD, MPH; Tracy Y. Wang, MD, MHS, MSc

This analysis of clinical data linked to Medicare claims finds the cardiac rehabilitation rate for older patients after acute myocardial infarction is low in the United States and suggests efforts be made for increasing referrals, and addressing attendance barriers, to rehabilitation sessions.

Invited Commentary: Closing the Treatment Gap for Cardiac Rehabilitation; Donna M. Polk, MD, MPH; Patrick T. O’Gara, MD
Ofer Merin, MD; Avraham Yitzhak, MD; Tarif Bader, MD

This Viewpoint identifies strategies for the appropriate and efficient emergency medical team assistance to other countries following natural disasters.

Mary K. Brennan-Taylor, BA

At 88 years of age, my mother, Alice, felt nagging pain in her neck and shoulders. She had been invited to several parties on July 4th and did not want the pain to crimp her enjoyment of the holiday. Her primary care physician’s office was closed for the ...

Original Investigation 
Steven B. Zeliadt, PhD, MPH; Jaimee L. Heffner, PhD; George Sayre, PsyD; Deborah E. Klein, MD; Carol Simons, BA; Jennifer Williams, BA; Lynn F. Reinke, PhD, APRN; David H. Au, MD, MS

Importance  Broad adoption of lung cancer screening may inadvertently lead to negative population health outcomes if it is perceived as a substitute for smoking cessation.

Objective  To understand views on smoking cessation from current smokers in the context of being offered lung cancer screening as a ...

Invited Commentary: The Psychological Effects of Lung Cancer Screening on Heavy Smokers ; Russell P. Harris, MD, MPH
Invited Commentary 
Russell P. Harris, MD, MPH

This Invited Commentary discusses the potential harms to heavy smokers undergoing screening for lung cancer.

The Belmont Report1 formally established ethical principles and guidelines in 1979 for the protection of human research subjects in the United States. Summarizing discussions among the National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research from an initial 4-day meeting at the Smithsonian ...

Our awareness of the potential adverse effects (AEs) of newly approved drugs and devices is limited. Premarket trials are often small and of limited duration, and the patients in clinical trials are healthier than unselected patients in routine clinical practice. Thus, the public and physicians rely on the ...

Research Letter 
Tanya Bhattacharya, BS; Debra G. Tice, MS; Pranathi Lingam, MD; Aleksandra Florek, MD; Eileen M. Yates, MS; Sigmund Weitzman, MD; Steven M. Belknap, MD

This database review assesses the disclosure to study participants of boxed warning risks on consent forms.

Editor's Note: Informed Consent and Research on Higher-Risk Medications; Joseph S. Ross, MD, MHS

Sign in

Purchase Options

• Subscribe to the journal
• Rent this article ?

A free personal account provides

• Free current issues on The JAMA Network Reader
• Free quizzes on The JAMA Network Challenge
• Commenting and personalized alerts