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 Showing 1-20 of 61 Articles
Mahmood Al-Abri, MD; Brian M. Wong, MD; Jerome A. Leis, MD, MSc
Simina R. Luca, MD; Mandana Kayedi, MD; Brian M. Wong, MD
Original Investigation 
Jennifer S. Haas, MD, MSc; Jeffrey A. Linder, MD, MPH; Elyse R. Park, PhD, MPH; Irina Gonzalez, MD, TTS; Nancy A. Rigotti, MD; Elissa V. Klinger, ScM; Emily Z. Kontos, ScD; Alan M. Zaslavsky, PhD; Phyllis Brawarsky, MPH; Lucas X. Marinacci, BA; Stella St Hubert, AB; Eric W. Fleegler, MD, MPH; David R. Williams, PhD, MPH

Importance  Widening socioeconomic disparities in mortality in the United States are largely explained by slower declines in tobacco use among smokers of low socioeconomic status (SES) than among those of higher SES, which points to the need for targeted tobacco cessation interventions. Documentation of smoking status in ...

Invited Commentary 
Anne Joseph, MD, MPH; Steven Fu, MD, MSCE
Most smokers want to quit smoking but try to stop without using tobacco cessation treatment. Because abundant evidence supports the efficacy of behavioral, pharmacologic, and combination treatment for tobacco dependence, it is important to increase the proportion of smokers who take advantage of therapy. Evidence confirms that current tobacco treatment ...
Editor's Note 
Joseph S. Ross, MD, MHS
In the United States, it has been estimated that in the past year more than one-third of adults used indoor tanning facilities, exposing themselves to high-pressure sunlamp products that emit UV light and radiation.1 Rates exceeded 50% among university students and were nearly 20% among adolescents. Unfortunately, it has taken ...
Research Letter 
Jae Moon Yun, MPH; Dong Wook Shin, MD, DrPH, MBA; Seung-sik Hwang, MD, PhD; Juhee Cho, MA, PhD; You Seon Nam, MD; Jung Hoe Kim, DrPH; Be Long Cho, MD, MPH, PhD
Although antibiotics are not required for treating uncomplicated upper respiratory tract infection (URTI),1 which is mostly viral, they are often prescribed, fueling antibiotic resistance and loss of protective flora. Accordingly, many studies worldwide have tried to decrease inappropriate antibiotic prescribing behavior.2
Research Letter 
Isla Rippon, MSc; Andrew Steptoe, DSc
Self-perceived age reflects appraisals of health, physical limitations, and well-being in later life.1 Older people typically feel younger than their chronologic age, and it is thought that those who feel younger than their actual age have reduced mortality.2,3 We sought to confirm this relationship in a large representative population sample, ...
Research Letter 
Gery P. Guy Jr, PhD, MPH; Meg Watson, MPH; Tadesse Haileyesus, MS; Joseph L. Annest, PhD, MS
Indoor tanning exposes users to intense UV radiation, which is a known carcinogen.1 However, little is known about the more immediate adverse outcomes of indoor tanning. To our knowledge, this study provides the first national estimates of indoor tanning–related injuries treated in US hospital emergency departments (EDs).
Tara Lagu, MD, MPH; Christine Griffin, JD; Peter K. Lindenauer, MD, MSc
Patients with disabilities face barriers when they attempt to access health care.1 These barriers include physical barriers to entering health care establishments, lack of accessible equipment, lack of a safe method for transferring the patient to an examination table, and the lack of policies that facilitate access.2 The barriers persist ...
Austin Lammers, MD; Read Pierce, MD
Marc G. Ghany, MD, MHSc
Chronic hepatitis C virus (HCV) infection accounts for approximately 30% of cases of cirrhosis and one-quarter of hepatocellular carcinomas worldwide and is the leading indication for liver transplant in the adult US population.1 Although the incidence of chronic HCV infection is declining in the United States, the number of deaths ...
Original Investigation 
Adeel A. Butt, MD, MS; Peng Yan, MS; Vincent Lo Re III, MD, MSCE; David Rimland, MD; Matthew B. Goetz, MD; David Leaf, MD, MPH; Matthew S. Freiberg, MD, MSc; Marina B. Klein, MD; Amy C. Justice, MD, PhD; Kenneth E. Sherman, MD, PhD; for the ERCHIVES (Electronically Retrieved Cohort of HCV Infected Veterans) Study Team
Includes: Supplemental Content

Importance  Knowing the rate of liver fibrosis progression in hepatitis C virus (HCV)-infected persons can help inform patients and providers (clinicians, medical institutions or organizations, and third-party payers) in making treatment decisions.

Objective  To determine the rate and factors associated with liver fibrosis progression and hepatic ...

Original Investigation  FREE
Jean-Pascal Fournier, MD, PhD; Laurent Azoulay, PhD; Hui Yin, MSc; Jean-Louis Montastruc, MD, PhD; Samy Suissa, PhD
Includes: Supplemental Content

Importance  Tramadol is a weak opioid analgesic whose use has increased rapidly, and it has been associated with adverse events of hypoglycemia.

Objective  To assess whether tramadol use, when compared with codeine use, is associated with an increased risk of hospitalization for hypoglycemia.

Design, Setting, and ...

Original Investigation 
Amit N. Vora, MD, MPH; DaJuanicia N. Holmes, MS; Ivan Rokos, MD; Matthew T. Roe, MD, MHS; Christopher B. Granger, MD; William J. French, MD, PhD; Elliott Antman, MD; Timothy D. Henry, MD; Laine Thomas, PhD; Eric R. Bates, MD; Tracy Y. Wang, MD, MHS, MSc
Includes: Supplemental Content

Importance  Guidelines for patients with ST-segment elevation myocardial infarction (STEMI) recommend timely reperfusion with primary percutaneous coronary intervention (pPCI) or fibrinolysis. Among patients with STEMI who require interhospital transfer, it is unclear how reperfusion strategy selection and outcomes vary with interhospital drive times.

Objective  To assess ...

Invited Commentary 
Lewis S. Nelson, MD; David N. Juurlink, MD, PhD
Pain is one of the leading reasons why patients seek medical attention, and over the past 2 decades, clinicians, health care institutions, medical organizations, and regulators have become increasingly attentive to its management. Yet despite the importance of pain as a clinical entity, the well of approved pharmacologic options is ...
Invited Commentary 
Marc J. Claeys, MD, PhD
The current guidelines for the management of ST-segment elevation myocardial infarction (STEMI) recommend primary percutaneous coronary intervention (pPCI) as the preferred treatment strategy if it can be conducted in a timely fashion by an experienced catheterization team.1 Because of the restricted availability of hospitals providing pPCI support 24 hours 7 ...
Research Letter 
Jonathan Bergman, MD, MPH; Christopher S. Saigal, MD, MPH; Mark S. Litwin, MD, MPH
Recently released Medicare physician utilization and payment data1 illuminate the reasons that physician payments from the Centers for Medicare & Medicaid Services vary. One could expect that while physician payments may vary widely based on the type of physician service, payments indexed to unique patients should not. In addition, physician ...
Research Letter 
Earl S. Ford, MD, MPH; Julie C. Will, PhD; Carla I. Mercado, PhD; Fleetwood Loustalot, PhD, FNP
Risk assessment has become an important tool to assess an individual’s future risk for cardiovascular disease. Recently, the American College of Cardiology/American Heart Association (ACC/AHA) released a report that presented updated risk equations, the Pooled Cohort Risk Equations, for cardiovascular disease.1 Race and ethnicity-specific estimates were novel to the new ...
Research Letter 
Catherine S. Hwang, MSPH; Lydia W. Turner, MHS; Stefan P. Kruszewski, MD; Andrew Kolodny, MD; G. Caleb Alexander, MD, MS
Chronic pain is one of the most common reasons for seeking medical attention in the United States, and such pain is frequently treated with prescription opioids. The clinical use of these products nearly doubled between 2000 and 2010,1 with simultaneous increases in the incidence of opioid abuse, addiction, injury, and ...
Christie Aschwanden
At a routine appointment a few days after my 40th birthday, my gynecologist gave me a prescription for a mammogram. There was no discussion, no explanation. Just a slip of paper, handed to me without a word as I left the examination room. When I asked the doctor what she’d ...

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