TY  - JOUR
T1  - ANaphylaxis
AU  - ANDERSON JF, ROSENAU MJ
Y1  - 1909/06/01
N1  - 10.1001/archinte.1909.00050160152012
JO  - Archives of Internal Medicine
SP  - 519
EP  - 568
VL  - III
IS  - 5
N2  - Anaphylaxis (ana, against, and phylax, guard, or phylaxis, protection), also called hypersusceptibility, supersensitiveness, is a condition of unusual or exaggerated susceptibility of the organism to foreign substances. The word "anaphylaxis" was introduced by Richet to describe a contrary condition to prophylaxis. As we now regard the phenomenon, the word is a misnomer, for we look upon the condition of hypersusceptibility as a distinct benefit and advantage to the organism. In fact, protection against a large class of infections depends on an altered power of reaction, i. e., hypersusceptibility or anaphylaxis.This state may be congenital or acquired, and is specific in nature. The condition of anaphylaxis may be brought about by the introduction of any strange protein into the body. Hypersusceptibility to proteins that are non-poisonous in themselves may readily be induced in certain animals.An animal may be in a condition of hypersusceptibility and
SN  - 0730-188X
M3  - doi: 10.1001/archinte.1909.00050160152012
UR  - http://dx.doi.org/10.1001/archinte.1909.00050160152012
ER  -