TY - JOUR T1 - CApsaicin cream unpopular with patients AU - Reinharth D Y1 - 2005/03/28 N1 - 10.1001/archinte.165.6.702 JO - Archives of Internal Medicine SP - 702 EP - 702 VL - 165 IS - 6 N2 - I found the recent article “Treatment Options in Knee Osteoarthritis”1 quite informative, particularly because it addressed a practical patient management issue. However, one key finding was discordant with my own experience managing this disease: in my practice, few patients have been willing to try treatment with capsaicin cream, and none has continued using it on a long-term basis. There are many barriers to the use of capsaicin: many patients prefer pills, 4 times daily dosing is difficult to comply with (this frequency is recommended for the first 2 weeks of use, as opposed to the 3 times daily “utility” the authors selected), and the cream burns (apparently ignored by the authors). It is my unscientific impression that my patients generally prefer treatment with acetaminophen (and cyclooxygenase-2 inhibitors before the recent troubles for this class of drugs) for their osteoarthritis. SN - 0003-9926 M3 - doi: 10.1001/archinte.165.6.702 UR - http://dx.doi.org/10.1001/archinte.165.6.702 ER -