TY  - JOUR
T1  - SPontaneous remission in cushing's disease
AU  - Ishibashi M, Shimada K, Abe K, Furue H, Yamaji T
Y1  - 1993/01/25
N1  - 10.1001/archinte.1993.00410020097009
JO  - Archives of Internal Medicine
SP  - 251
EP  - 255
VL  - 153
IS  - 2
N2  - Two patients with Cushing's disease underwent spontaneous clinical and biochemical remission following a period of secondary adrenal insufficiency. One of the patients was untreated, while the other had been treated with partial bilateral adrenalectomy before. Both patients underwent remission shortly after the administration of dexamethasone for diagnostic purposes and remained symptom free for 2 and 3 years, respectively, which was followed by relapse of the disease. We conclude that although resolution of Cushing's disease may occur spontaneously, probably by hemorrhagic infarction of corticotroph microadenomas, careful follow-up studies are required since the relapse of the disease occurs later in some patients.(Arch Intern Med. 1993;153:251-255)
SN  - 0003-9926
M3  - doi: 10.1001/archinte.1993.00410020097009
UR  - http://dx.doi.org/10.1001/archinte.1993.00410020097009
ER  -