TY  - JOUR
T1  - A new noninvasive management strategy for patients with suspected pulmonary embolism
AU  - Hull RD, Raskob GE, Coates G, Panju AA, Gill GJ
Y1  - 1989/11/01
N1  - 10.1001/archinte.1989.00390110105024
JO  - Archives of Internal Medicine
SP  - 2549
EP  - 2555
VL  - 149
IS  - 11
N2  - • Pulmonary embolism is associated strongly with proximalvein thrombosis. We tested the hypothesis that recurrent venous thromboembolism is unlikely in the absence of proximal-vein thrombosis. We performed a prospective cohort study in 874 patients with suspected pulmonary embolism. On long-term follow-up of 371 patients with the following characteristics: (1) abnormal, non–high-probability lung scans, (2) off anticoagulant therapy, and (3) serial noninvasive test results negative for proximal-vein thrombosis, only 10 (2.7%; 95% confidence limits, 1.3% to 4.9%) had venous thromboembolism. By comparison, venous thromboembolism on follow-up occurred in 3(1%) of 315 patients (95% confidence limits, 0.2% to 2.8%) with normal lung scans, and in 5(7%) of 66 patients (95% confidence limits, 2.5% to 16.8%) with high-probability lung scans. Patients whose serial noninvasive test results were negative for proximal-vein thrombosis have a good prognosis without anticoagulant therapy.(Arch Intern Med. 1989;149:2549-2555)
SN  - 0003-9926
M3  - doi: 10.1001/archinte.1989.00390110105024
UR  - http://dx.doi.org/10.1001/archinte.1989.00390110105024
ER  -