TY - JOUR T1 - A preliminary report of the short-term effect of carbonated beverage consumption on calcium metabolism in normal women AU - Smith S, Swain J, Brown EM, et al Y1 - 1989/11/01 N1 - 10.1001/archinte.1989.00390110089020 JO - Archives of Internal Medicine SP - 2517 EP - 2519 VL - 149 IS - 11 N2 - • A variety of nutritional factors influence the bioavailability of calcium and increase a woman's risk of osteoporosis. Eight healthy women completed an 8-week metabolic study designed to investigate the effect of nonalcoholic carbonated beverage consumption on calcium metabolism. Compared with women receiving a control diet, women consuming a diet high in nonalcoholic carbonated beverages demonstrated similar mean serum levels of calcium, ionized calcium, phosphorus, alkaline phosphatase, parathyroid hormone, 1,25-dihydroxyvitamin D3, and osteocalcin. Twenty-four-hour urine volume, creatinine clearance, calcium-creatinine ratio, and phosphorus-creatlnine ratio were similar during consumption of the diet high in nonalcoholic carbonated beverages and the control diet. Twenty-fourhour cyclic adenosine monophosphate–creatinine ratio was significantly lower in women consuming the diet high in nonalcoholic carbonated beverage compared with women receiving the control diet (342±27.4 nmol/mmol vs 409±22.1 nmol/mmol). Consumption of a diet high in nonalcoholic carbonated beverages on a short-term basis does not appear to affect adversely the serum or urinary markers of calcium metabolism.(Arch Intern Med. 1989;149:2517-2519) SN - 0003-9926 M3 - doi: 10.1001/archinte.1989.00390110089020 UR - http://dx.doi.org/10.1001/archinte.1989.00390110089020 ER -