TY  - JOUR
T1  - AN ecogenetic hypothesis for lung cancer in women-reply
AU  - HORWITZ RI, VISCOLI CM, SMALDONE LF
Y1  - 1989/08/01
N1  - 10.1001/archinte.1989.00390080144034
JO  - Archives of Internal Medicine
SP  - 1900
EP  - 1900
VL  - 149
IS  - 8
N2  - In Reply.—We are pleased to respond to the comments of Drs Ness and Price, especially since they have restated concerns that we noted in our article, "An Ecogenetic Hypothesis for Lung Cancer in Women."1 We were also concerned that clinicians conducting interviews of hospitalized patients may be more likely to ask and record data about a family history of lung cancer for cases rather than for control subjects. To minimize bias from this problem, we chose only control subjects who had family history data in the record. While we would prefer structured interviews with patients (cases and control subjects), we believe our approach is preferable to collecting control data without recorded family history. We do not agree with Drs Ness and Price that assessing family risk "..... in terms of number of lung cancers among an explicitly defined number of relatives at risk" is a superior strategy. Restricting family history
SN  - 0003-9926
M3  - doi: 10.1001/archinte.1989.00390080144034
UR  - http://dx.doi.org/10.1001/archinte.1989.00390080144034
ER  -