TY  - JOUR
T1  - ß-blockers and cognitive performance in older patients
AU  - MINTZER J
Y1  - 1989/05/01
N1  - 10.1001/archinte.1989.00390050167044
JO  - Archives of Internal Medicine
SP  - 1223
EP  - 1224
VL  - 149
IS  - 5
N2  - To the Editor.—I read with interest the recent article in the Archives by Gengo and colleagues1 on "The effect of β-blockers on mental performance on older hypertensive patients." These findings seem to confirm previous studies by Eisdorfer et al2-4 and Wilkie et al5 on learning and autonomic activity.In these studies, Eisdorfer and colleagues3 determined the extent of heightened and persistent autonomic activation in older men as reflected by elevated levels of free fatty acid. Elderly men evidenced elevated levels of free fatty acid relative to younger men and exhibited a delay in returning to baseline free fatty acid levels when confronted with a learning task.Moreover, cognitive impairment among older men was associated with autonomic hyperarousal4 and learning
SN  - 0003-9926
M3  - doi: 10.1001/archinte.1989.00390050167044
UR  - http://dx.doi.org/10.1001/archinte.1989.00390050167044
ER  -