TY  - JOUR
T1  - PRimary care medicine
Y1  - 1979/11/01
N1  - 10.1001/archinte.1979.03630480003002
JO  - Archives of Internal Medicine
SP  - 1209
EP  - 1212
VL  - 139
IS  - 11
N2  - Thyrotoxicosis and atrial fibrillation 
    It has been known that overt clinical thyrotoxicosis is one cause of persistent atrial fibrillation. Now, a team of Scottish physicians is using sensitive laboratory tests to show that more subtle, subclinical thyrotoxicosis also causes atrial fibrillation.These investigators report (Am J Cardiol 44:9-12, 1979) that, among 75 persons with sustained atrial fibrillation referred to the cardiology clinic of the Royal Infirmary, Edinburgh, (none of whom had detectable cardiovascular disease), only two were suspected of having thyrotoxicosis. All 75 patients were tested for an increase in thyroid-stimulating hormone (thyrotropin) in response to administration of thyrotropin-releasing hormone (TRH). Ten patients (13%) were diagnosed as thyrotoxic on the basis of a lack of response in this test. Two patients had more than a modest elevation in the serum level of the thyroid hormones.All ten thyrotoxic patients were treated with antithyroid drugs, either131I or carbimazole.
SN  - 0003-9926
M3  - doi: 10.1001/archinte.1979.03630480003002
UR  - http://dx.doi.org/10.1001/archinte.1979.03630480003002
ER  -