TY  - JOUR
T1  - ANterior pituitary hormones in csf
AU  - Randall RV
Y1  - 1979/10/01
N1  - 10.1001/archinte.1979.03630470014007
JO  - Archives of Internal Medicine
SP  - 1092
EP  - 1092
VL  - 139
IS  - 10
N2  - After the initial report by Linfoot and co-workers in 1970,1 it has been assumed that an abnormal increase in the concentration of an anterior pituitary hormone in the CSF is indicative of suprasellar extension of the pituitary tumor producing that hormone. The report by Jordan et al in the February issue of the Archives (139:208-211, 1979) and a recent corroborative report by Assies and associates2 show that prolactin is an exception to this assumption, and that substantial elevations of prolactin levels in the CSF can be found in association with a prolactin-producing tumor that has no demonstrable suprasellar extension. This was also noted in one of the patients described by Schroeder et al.3 Furthermore, all three groups of authors showed that CSF prolactin level is increased at term in pregnant women who are not known to have pituitary abnormalities. Assies et al also found that patients with
SN  - 0003-9926
M3  - doi: 10.1001/archinte.1979.03630470014007
UR  - http://dx.doi.org/10.1001/archinte.1979.03630470014007
ER  -