TY - JOUR T1 - GLucocorticoid effects in vitamin d intoxication AU - Streck WF, Waterhouse C, Haddad JG Y1 - 1979/09/01 N1 - 10.1001/archinte.1979.03630460018009 JO - Archives of Internal Medicine SP - 974 EP - 977 VL - 139 IS - 9 N2 - Calcium balance studies and measurement of 25-hydroxyvitamin D (25[OH]D 3) levels were performed on a vitamin D intoxicated, hypoparathyroid patient before, during, and after successful management of hypercalcemia with oral prednisone therapy. Prednisone effected a dramatic reduction in both mean serum calcium levels and mean 24-hour urinary calcium excretion within four days on two separate occasions. No changes were apparent in fecal calcium excretion. Calcium balance became less negative with prednisone treatment. Levels of 25(OH) D during the same period did not change. Decreased calcium mobilization from bone best accounted for the glucocorticoid-mediated amelioration of hypercalcemia.(Arch Intern Med 139:974-977, 1979) SN - 0003-9926 M3 - doi: 10.1001/archinte.1979.03630460018009 UR - http://dx.doi.org/10.1001/archinte.1979.03630460018009 ER -