TY  - JOUR
T1  - MAnagement of alcohol withdrawal syndromes
AU  - Karis R
Y1  - 1979/08/01
N1  - 10.1001/archinte.1979.03630450087036
JO  - Archives of Internal Medicine
SP  - 945
EP  - 945
VL  - 139
IS  - 8
N2  - To the Editor.— 
    Thompson, in the February 1978 Archives (138:278-283), reviews six studies1-6 of the treatment of alcohol withdrawal and concludes that "sedatives stopped progression of early withdrawal to... DTs [delirium tremens]." My analysis of the same six studies yields different results.Two of these studies1,6 are not applicable to the point in question. One report6 evaluates the treatment of DTs and not its prevention. In the other article,1 the frequency of occurrence of DTs is not clear.The results of the remaining four studies are summarized in the Table. Obviously, it is difficult to combine the results of such disparate studies with varying experimental designs, utilization of different dosages, times, routes of administration of medication, and other such considerations. As is evident from the Table, no statistically significant differences are found between the various types of treatment.Many theoretical considerations are relevant to the lack
SN  - 0003-9926
M3  - doi: 10.1001/archinte.1979.03630450087036
UR  - http://dx.doi.org/10.1001/archinte.1979.03630450087036
ER  -