TY  - JOUR
T1  - LIver disease in early syphilis
AU  - Campisi D, Whitcomb C
Y1  - 1979/03/01
N1  - 10.1001/archinte.1979.03630400079028
JO  - Archives of Internal Medicine
SP  - 365
EP  - 366
VL  - 139
IS  - 3
N2  - Atypical manifestations of early syphilis, although uncommon, may represent diagnostic difficulties and delay therapy. We describe two cases of hepatitis complicating early syphilis. Clues to the diagnosis of early syphilitic hepatitis include the presence of perianal lesions and disproportionate increases in the serum alkaline phosphatase level. Biopsy results were nonspecific. The major differential diagnostic consideration is hepatitis B with false-positive serologic findings. The abnormalities of liver function respond to standard therapy for secondary syphilis. Follow-up of patients and their contacts is essential.(Arch Intern Med 139:365-366, 1979)
SN  - 0003-9926
M3  - doi: 10.1001/archinte.1979.03630400079028
UR  - http://dx.doi.org/10.1001/archinte.1979.03630400079028
ER  -