TY - JOUR T1 - MEtronidazole therapy of anaerobic bacteremia, meningitis, and brain abscess AU - Warner JF, Perkins RL, Cordero L Y1 - 1979/02/01 N1 - 10.1001/archinte.1979.03630390027013 JO - Archives of Internal Medicine SP - 167 EP - 169 VL - 139 IS - 2 N2 - Four patients with Bacteroides fragilis bacteremia, one patient with a brain abscess due to Bacteroides species, Fusobacterium naviforme, and Peptostreptococcus species, and an infant with Bacteroides species ventriculitis and meningitis were treated with metronidazole. In all cases the anaerobic pathogens were eradicated. Five of the six patients recovered. One patient with leukemia in whom B fragilis bacteremia was eradicated by metronidazole treatment subsequently died of Pseudomonas aeruginosa bacteremia. Ventricular fluid and serum concentrations of metronidazole were determined in the case of meningitis and are reported.(Arch Intern Med 139:167-169, 1979) SN - 0003-9926 M3 - doi: 10.1001/archinte.1979.03630390027013 UR - http://dx.doi.org/10.1001/archinte.1979.03630390027013 ER -