TY - JOUR T1 - ENdocrine studies in patients with the "empty sella syndrome" AU - Caplan RH, Dobben GD Y1 - 1969/06/01 N1 - 10.1001/archinte.1969.00300160001001 JO - Archives of Internal Medicine SP - 611 EP - 619 VL - 123 IS - 6 N2 - During a 12-month period, 17 patients with enlarged sellae turcicae underwent pneumoencephalography and endocrine function tests prior to radiation therapy. In five of these patients, and in a patient for whom the diagnosis had been made previously, substantial amounts of injected air extended into the sella turcica. This syndrome occurred spontaneously in five patients and developed 14 years after radiation treatment for acromegaly in another. Various degrees of pituitary hormone dysfunction were noted in four of six patients. SN - 0003-9926 M3 - doi: 10.1001/archinte.1969.00300160001001 UR - http://dx.doi.org/10.1001/archinte.1969.00300160001001 ER -