TY - JOUR T1 - MAjor endocrine surgery for the treatment of cancer of the breast in advanced stages. AU - Ultmann JE Y1 - 1969/04/01 N1 - 10.1001/archinte.1969.00300140122037 JO - Archives of Internal Medicine SP - 476 EP - 476 VL - 123 IS - 4 N2 - One hundred seventeen experts have contributed to a review of the present status of endocrine surgery in the management of advanced cancer of the breast. The present volume is the result of a meeting held in Lyon, France, May 5 to 7, 1966. Introduced by Huggins and opened with a paper by Dao, the symposium volume brings together the results obtained in a number of medical centers with adrenalectomies, adrenal-splenic transplantation, and surgical and radioactive hypophysectomies. In addition, sections are devoted to fundamental biological studies and a comparison of medical and surgical techniques for the control of breast cancer.In over 2,600 bilateral adrenalectomies, objective responses were obtained in 15% to 38% of cases, with an operative mortality of 2.7% to 4%. In more than 1,500 hypophysectomies, objective improvement occurred in 19% to 38% of cases, with an operative mortality of up to 6%. The variability of response emphasizes the SN - 0003-9926 M3 - doi: 10.1001/archinte.1969.00300140122037 UR - http://dx.doi.org/10.1001/archinte.1969.00300140122037 ER -