TY  - JOUR
T1  - BLood glucose and gluconeogenesis in fasting man
AU  - Felig P, Marliss E, Owen OE, Cahill GF, Jr.
Y1  - 1969/03/01
N1  - 10.1001/archinte.1969.00300130075011
JO  - Archives of Internal Medicine
SP  - 293
EP  - 298
VL  - 123
IS  - 3
N2  - Maintenance of blood glucose homeostasis in fasting man requires establishment of a fine balance between glucose production and utilization. Early in starvation, a decrease in serum insulin provides the alterations in substrate concentration and enzymatic activity conducive to augmented gluconeogenesis. As fasting progresses, glucose utilization is reduced as the brain consumes ketone bodies. A concomitant reduction in total gluconeogenesis is brought about by a reduction in plasma amino acid levels, particularly alanine.
SN  - 0003-9926
M3  - doi: 10.1001/archinte.1969.00300130075011
UR  - http://dx.doi.org/10.1001/archinte.1969.00300130075011
ER  -