TY  - JOUR
T1  - KEratosis palmaris et plantaris
AU  - FRED HL, GIESER RG, BERRY WR, EIBAND JM
Y1  - 1964/06/01
N1  - 10.1001/archinte.1964.00280120066012
JO  - Archives of Internal Medicine
SP  - 866
EP  - 871
VL  - 113
IS  - 6
N2  - Keratosis palmaris et plantaris (KPP), also referred to as tylosis and by many other synonyms,* is a heredofamilial ectodermal defect characterized by hyperkeratosis of the palms and soles. Since KPP ordinarily is not accompanied by systemic manifestations or specific lesions of internal organs, the internist rarely encounters the syndrome. Therefore, the purpose of this report is to review briefly the subject of KPP and to present one of the most extraordinary examples of this malady ever recorded.Report of a Case 
    A 56-year-old Latin-American mechanic was admitted to The Ben Taub General Hospital because of hematemesis of one day's duration. There had been no associated abdominal pain, jaundice, black stools, weight loss, recent intake of alcohol, or previous episodes of gastrointestinal bleeding. The patient had been a "spree drinker" in the past.The only significant feature of the past medical history was that of palmar and plantar hyperkeratosis. Neither the
SN  - 0003-9926
M3  - doi: 10.1001/archinte.1964.00280120066012
UR  - http://dx.doi.org/10.1001/archinte.1964.00280120066012
ER  -