TY  - JOUR
T1  - THe management of parkinson's disease
AU  - ENGLAND AC, Jr., SCHWAB RS
Y1  - 1959/09/01
N1  - 10.1001/archinte.1959.00270090093017
JO  - A.M.A. Archives of Internal Medicine
SP  - 439
EP  - 468
VL  - 104
IS  - 3
N2  - I. Historical Review 
    In 1817, James Parkinson 1 described six cases of the condition which now bears his name. These were all men with a disease state he characterized by tremor, loss of finger and arm dexterity, propulsion, festination and falling, insomnia, constipation, and dorsal kyphosis. Finally, there came on aphonia, dysphagia, and incontinence. From reading the text, it is apparent that these cases had generalized slowness of movement and marked dependence on others for the ordinary tasks such as eating, dressing, and walking. Rigidity is curiously not mentioned, but it is fair to say that it must have been present in order that the other symptoms might appear. The following quotation will remind present-day students of the acuity of his observations:.... [p. 3] The first symptoms perceived are, a slight sense of weakness with a proneness to trembling in some particular part; sometimes in the head but most commonly
SN  - 0888-2479
M3  - doi: 10.1001/archinte.1959.00270090093017
UR  - http://dx.doi.org/10.1001/archinte.1959.00270090093017
ER  -