TY - JOUR T1 - MYocardial infarction as the initial manifestation of polycythemia vera AU - VACCA JB, THOMA GE, Jr. Y1 - 1959/06/01 N1 - 10.1001/archinte.1959.00270060126017 JO - A.M.A. Archives of Internal Medicine SP - 974 EP - 977 VL - 103 IS - 6 N2 - Vascular occlusions occur rather frequently in polycythemia vera. While venous thromboses are said to be commoner, arterial occlusion or insufficiency has been reported to occur in approximately 18% to 30% of several series.1-4 While at least one earlier report concluded that cardiac disease was uncommon in polycythemia vera,5 later articles have shown coronary artery disease to occur clinically in from 6% to 10% of cases 1,4,6 and to be the cause of death in approximately one-fourth of a small series prior to the use of radioactive phosphorus in therapy.3Myocardial infarction occurring early in the course of polycythemia vera is apparently rare; we have been able to discover but one brief reference to the occurrence of this complication, in a previously undiagnosed (and presumably asymptomatic) case.7 The purpose of this communication is to report a 41-year-old patient who was discovered to have asymptomatic polycythemia vera at the time he had SN - 0888-2479 M3 - doi: 10.1001/archinte.1959.00270060126017 UR - http://dx.doi.org/10.1001/archinte.1959.00270060126017 ER -