TY  - JOUR
T1  - ACquired agammaglobulinemia with multiple allergies and pernicious anemia
AU  - CROWDER R, Jr., THOMPSON WT, Jr., KUPFER HG
Y1  - 1959/03/01
N1  - 10.1001/archinte.1959.00270030101010
JO  - A.M.A. Archives of Internal Medicine
SP  - 445
EP  - 452
VL  - 103
IS  - 3
N2  - A number of cases of agammaglobulinemia have been reported in the medical literature since Bruton1 described the first case in 1952. This condition is encountered more frequently because patients who are unable to produce antibodies against infection are surviving now with the aid of antibiotics. It is recognized more readily because a high index of suspicion of this is becoming widespread, and methods of establishing the diagnosis by the study of serum proteins are now available to most physicians.Two forms of isolated agammaglobulinemia exist: (1) a congential type. occuring as a recessive sex-linked trait in male children, with symptoms developing reduced form the normal of approximately 1,000 mg. % to less than 10 mg. %, and (2) an acquired type occurring in either sex, with symptoms developing in adulthood and serum γ-globulin levels of 20-40 mg. %. Such a distinction may be arbitrary and more apparent than real, for
SN  - 0888-2479
M3  - doi: 10.1001/archinte.1959.00270030101010
UR  - http://dx.doi.org/10.1001/archinte.1959.00270030101010
ER  -