TY  - JOUR
T1  - Recession of neuroretinopathy during the course of malignant hypertension: Its occurrence in fifteen patients who did not receive directed therapy
AU  - KEITH NM, WAGENER HP
Y1  - 1951/01/01
N1  - 10.1001/archinte.1951.03810010035004
JO  - A.M.A. Archives of Internal Medicine
SP  - 25
EP  - 47
VL  - 87
IS  - 1
N2  - WE DESCRIBED in 19241 a clinical syndrome that occurred in a small group of patients who had had severe hypertension and neuroretinopathy. The further course of the disease was progressive, often rapidly fatal, and led us to apply the term syndrome of malignant hypertension to the condition. Our clinical and pathological studies suggested that the widespread involvement of many viscera was due to diffuse alterations in the arteriolar system.2 With increasing experience in subsequent cases, we 3 and others4 on rare occasions observed a patient in whom the disease appeared to be arrested and recession of the papilledema and of the retinopathy had occurred. Over a period of 20 years, we have seen the subsidence of the retinopathy in 15 patients and at the time of the observation were unable to offer a satisfactory explanation for this favorable turn of events.Other investigators have reported recession of
SN  - 0888-2479
M3  - doi: 10.1001/archinte.1951.03810010035004
UR  - http://dx.doi.org/10.1001/archinte.1951.03810010035004
ER  -