TY - JOUR T1 - FUlminant toxic epidermal necrolysis induced by trovafloxacin AU - Matthews MR, Caruso DM, Phillips BJ, Csontos LG Y1 - 1999/10/11 N1 - JO - Archives of Internal Medicine SP - 2225 EP - 2225 VL - 159 IS - 18 N2 - Toxic epidermal necrolysis (TEN) is a devastating full-thickness epidermal exfoliative disease caused by an inciting medication.1 Clinical evidence of the disease usually presents 1 to 2 weeks after administration of the inciting medication. However, upon reexposure to a medication that previously caused TEN or exposure to a structurally related compound, the subsequent reaction is fulminant, is more severe, and may occur after the first dose.2 Although TEN has been documented after exposure to quinolones, the incidence is very low.3 SN - 0003-9926 M3 - doi: UR - http://dx.doi.org/ ER -