TY - JOUR T1 - MIght cold adaptation reduce cardiovascular mortality during winter? AU - De Lorenzo F, Kakkar VV Y1 - 1999/09/13 N1 - JO - Archives of Internal Medicine SP - 1954 EP - 1954 VL - 159 IS - 16 N2 - The mechanisms by which abrupt rupture of atherosclerotic plaques occur during cold exposure have been associated with an increased sympathetic activity that causes increased blood pressure, heart rate, and cardiac workload.2 In addition, increased serum lipids levels,3 plasma viscosity,4 fibrinogen values,3,5 factor VII:c levels,5 and platelet counts have been reported.4 Therefore, several authors have concluded that the effect of cold weather during winter on cardiovascular mortality was mediated by the increase of these risk factors.3- 5 SN - 0003-9926 M3 - doi: UR - http://dx.doi.org/ ER -