TY - JOUR T1 - A surfeit of serotonin: Sumatriptan and serotonergic antidepressants AU - Schwartz CE Y1 - 1999/05/24 N1 - JO - Archives of Internal Medicine SP - 1141 EP - 1141 VL - 159 IS - 10 N2 - The article by Knudsen et al1 presents their astute clinical observation of a series of 8 cases of ischemic colitis in patients being treated with sumatriptan succinate. This is a heretofore unreported association and represents a potentially critical side effect involving extracranial vasoconstriction. In speculating about the cause, the authors discuss the possibility of drug-drug interactions, noting that 7 of the 8 patients in their series were taking other concurrent medication(s) in addition to the sumatriptan. SN - 0003-9926 M3 - doi: UR - http://dx.doi.org/ ER -