TY - JOUR T1 - PRevalence of subtle cobalamin deficiency AU - Lesho EP, Hyder A Y1 - 1999/02/22 N1 - JO - Archives of Internal Medicine SP - 407 EP - 407 VL - 159 IS - 4 N2 - The prevalence of cobalamin deficiency has ranged from 3% to 29%.1- 3 Subtle cobalamin deficiency is defined as metabolic evidence of cobalamin deficiency, such as elevated serum or urine methylmalonate levels, or abnormal findings on a deoxyuridine suppression test, or the absence of neurological symptoms or megaloblastic anemia.4 The prevalence of subtle cobalamin deficiency is unknown, but in one elderly population was 39%.1 Concerns have been raised regarding the initiation of widespread folate supplementation because it might obscure the hematologic effects of cobalamin deficiency and facilitate the progression of neuropsychiatric damage.4- 5 SN - 0003-9926 M3 - doi: UR - http://dx.doi.org/ ER -