TY  - JOUR
T1  - GAstroesophageal reflux disease stimulation of nsaid-associated atrial fibrillation
AU  - Daniell HW
Y1  - 2011/04/11
N1  - 10.1001/archinternmed.2011.107
JO  - Archives of Internal Medicine
SP  - 702
EP  - 710
VL  - 171
IS  - 7
N2  - 
The association between atrial fibrillation (AF) and nonsteroidal anti-inflammatory drug (NSAID) use demonstrated by De Caterina et al1 may be augmented by at least 2 common mechanisms not included among those that they proposed. Reflux esophagitis is extremely common during NSAID use and has been independently associated with AF2; its treatment with protein pump inhibitors (PPIs) has been associated with less frequent AF.3- 4 Prolonged, habitual, physical effort, which may increase NSAID use, may also induce a much greater frequency of AF,5 potentially contributing to the NSAID-AF association.

SN  - 0003-9926
M3  - doi: 10.1001/archinternmed.2011.107
UR  - http://dx.doi.org/10.1001/archinternmed.2011.107
ER  -