TY  - JOUR
T1  - UNexpectedly high ptt values after low-dose heparin prophylaxis
AU  - Fiebig EW, Jones M, Logan A, Wang CS, Lewis B
Y1  - 2011/04/11
N1  - 10.1001/archinternmed.2011.106
JO  - Archives of Internal Medicine
SP  - 702
EP  - 710
VL  - 171
IS  - 7
N2  - 
Thromboembolic (TE) prophylaxis using low-dose unfractionated heparin (LD-UFH), ie, 5000 IU given subcutaneously twice or 3 times daily is effective, has low bleeding risk, and is generally not expected to prolong partial thromboplastin times (PTTs). Laboratory monitoring or dose adjustments based on weight or renal function are not considered necessary.1 An index case at our institution prompted us to review this conventional view and investigate the frequency and circumstances when significant PTT prolongations occur in hospitalized patients receiving LD-UFH for TE prophylaxis.

SN  - 0003-9926
M3  - doi: 10.1001/archinternmed.2011.106
UR  - http://dx.doi.org/10.1001/archinternmed.2011.106
ER  -