TY - JOUR T1 - BUprenorphine as a safety net for opioid treatment of nonmalignant pain AU - Kornfeld H Y1 - 2011/03/28 N1 - 10.1001/archinternmed.2011.83 JO - Archives of Internal Medicine SP - 596 EP - 597 VL - 171 IS - 6 N2 - Believers in opioid therapy for CNCP were influenced by a noble impulse to right a series of wrongs. Following decades of opioid excesses, the federal government seized control of opioid prescribing between 1915 and 1920 and severe opiophobia ensued, leading to the neglect of patients, the criminalization of addiction, and the prosecution of physicians. Even as the undertreatment of pain still persists for many populations throughout the world, the pendulum is now swinging back to fears of opioid's hazards in CNCP, particularly when a morphine equivalent dose exceeds a threshold of 100 to 200 mg. SN - 0003-9926 M3 - doi: 10.1001/archinternmed.2011.83 UR - http://dx.doi.org/10.1001/archinternmed.2011.83 ER -