TY - JOUR T1 - Lifestyle and adiponectin level: Four-year follow-up of controlled trials AU - Esposito K, Giugliano D Y1 - 2010/07/26 N1 - 10.1001/archinternmed.2010.246 JO - Archives of Internal Medicine SP - 1270 EP - 1271 VL - 170 IS - 14 N2 - The adiponectin adipocyte-secreted adipokine has both insulin-enhancer and anti-inflammatory properties1 and is the most consistent biochemical predictor of type 2 diabetes mellitus. Higher adiponectin levels are consistently associated with a lower risk of type 2 diabetes in 13 prospective studies of diverse populations with a total of 14 598 participants and 2623 incident cases of type 2 diabetes, with a relative risk of 0.72 (95% confidence interval, 0.67-0.78) per 1-log μg/mL increment in adiponectin levels.2 Identification of lifestyle changes able to increase adiponectin circulating levels may help refine the strategy against the current diabetes epidemics. SN - 0003-9926 M3 - doi: 10.1001/archinternmed.2010.246 UR - http://dx.doi.org/10.1001/archinternmed.2010.246 ER -