TY - JOUR T1 - Screening for depression: This is the heart of the matter AU - Grissom GR, Phillips RA Y1 - 2005/06/13 N1 - 10.1001/archinte.165.11.1214 JO - Archives of Internal Medicine SP - 1214 EP - 1215 VL - 165 IS - 11 N2 - Despite Hippocrates’ advice, few clinicians and researchers have suspected that psychological problems may be among the most important modifiable risk factors for medical morbidity and mortality. There is growing evidence that this could be the case. Many cardiac patients (30%-45%) experience clinically important depressive symptoms.1 The impact of depression on cardiac outcomes is at least as important as a history of myocardial infarction and left ventricular dysfunction.2 Depression is related to onset of cardiac disease; it is associated with higher medical costs; and it reduces patients’ quality of life and compliance with treatment.3- 5 The cardiovascular prognosis is linked to the severity of depressive symptoms6: risk increases along with symptom severity whether or not the patient meets diagnostic criteria for a depressive disorder.7 SN - 0003-9926 M3 - doi: 10.1001/archinte.165.11.1214 UR - http://dx.doi.org/10.1001/archinte.165.11.1214 ER -