TY  - JOUR
T1  - ATovaquone-proguanil use in early pregnancy and the risk of birth defects
AU  - Björn P, Anders H
Y1  - 2011/02/14
N1  - 10.1001/archinternmed.2010.521
JO  - Archives of Internal Medicine
SP  - 259
EP  - 260
VL  - 171
IS  - 3
N2  - 
Malaria infection in pregnancy is associated with increased risk of complications for the mother and fetus,1 particularly in individuals not previously exposed to malaria, eg, travelers. Pregnant women are advised to avoid travel to countries where there is elevated risk of contracting malaria.2- 3 For pregnant individuals who still choose to or must travel to malaria-endemic areas where there is chloroquine resistance, currently none of the available prophylactic drugs are recommended in early pregnancy. This is either owing to adverse fetal effects (doxycycline), paucity of safety data (mefloquine), or absence of such (atovaquone-proguanil).2- 4

SN  - 0003-9926
M3  - doi: 10.1001/archinternmed.2010.521
UR  - http://dx.doi.org/10.1001/archinternmed.2010.521
ER  -