TY - JOUR T1 - PEritoneal tuberculosis after imatinib therapy AU - Senn L, Kovacsovics T, Tarr PE, Meylan P Y1 - 2009/02/09 N1 - 10.1001/archinternmed.2008.581 JO - Archives of Internal Medicine SP - 312 EP - 316 VL - 169 IS - 3 N2 - Imatinib mesylate, a selective inhibitor of the BCR-ABL tyrosine kinase gene, is now a standard therapy in patients with chronic myeloid leukemia (CML) and gastrointestinal stromal tumor (GIST). Recent studies have shown that imatinib alters T-cell–mediated immune responses,1- 4 raising the possibility of opportunistic infections associated with imatinib therapy. So far, few epidemiological data are available to support this hypothesis. We report herein a case of peritoneal tuberculosis (TB) following 4 months of imatinib therapy for CML. SN - 0003-9926 M3 - doi: 10.1001/archinternmed.2008.581 UR - http://dx.doi.org/10.1001/archinternmed.2008.581 ER -