TY - JOUR T1 - MOrphine is not a sedative and does not shorten life AU - Kompanje EO, van Zuylen L, van der Rijt C Y1 - 2006/10/09 N1 - 10.1001/archinte.166.18.2047-a JO - Archives of Internal Medicine SP - 2047 EP - 2047 VL - 166 IS - 18 N2 - Palliative sedation is considered to be an effective treatment for dispelling refractory symptoms in patients near death. Benzodiazepines such as midazolam are proper sedatives for palliative care for patients with refractory symptoms such as delirium and terminal agitation. Palliation of pain or dyspnea first requires opioids. Although many palliative patients receive opioids prior to the initiation of palliative sedation, opioids are empirically not effective at producing sustained sedation. SN - 0003-9926 M3 - doi: 10.1001/archinte.166.18.2047-a UR - http://dx.doi.org/10.1001/archinte.166.18.2047-a ER -