TY - JOUR T1 - Serum α-carotene concentrations and risk of death among us adults: The third national health and nutrition examination survey follow-up study AU - Li C, Ford ES, Zhao G, Balluz LS, Giles WH, Liu S Y1 - 2011/03/28 N1 - 10.1001/archinternmed.2010.440 JO - Archives of Internal Medicine SP - 507 EP - 515 VL - 171 IS - 6 N2 - Oxidative damage to DNA, proteins, and lipids may play an important role in the pathogenesis of some chronic diseases, including cardiovascular disease (CVD) and cancer.1 In vitro study results have suggested that antioxidants directly scavenge reactive oxygen and nitrogen species and thus delay or prevent oxidative damage.1 Carotenoids (α-carotene, β-carotene, lycopene, lutein, β-cryptoxanthin, zeaxanthin, and astaxanthin) are potent antioxidants that are synthesized by plants and microorganisms.2 The circulating carotenoids in the human body are obtained mainly through consumption of fruits and vegetables that are rich in carotenoids or antioxidant supplements containing β-carotene.3 SN - 0003-9926 M3 - doi: 10.1001/archinternmed.2010.440 UR - http://dx.doi.org/10.1001/archinternmed.2010.440 ER -