TY - JOUR T1 - ALlhat findings revisited in the context of subsequent analyses, other trials, and meta-analyses—reply AU - Wright JT, Jr, Probstfield JL, Cushman WC, et al Y1 - 2009/10/26 N1 - 10.1001/archinternmed.2009.372 JO - Archives of Internal Medicine SP - 1806 EP - 1818 VL - 169 IS - 19 N2 - We appreciate the favorable comments by Dr Onuigbo on this latest ALLHAT publication.1 We were also impressed by the very positive findings in thiazide-treated patients. ALLHAT was designed to determine whether α-blockers, ACEIs, or CCBs were superior to thiazide-type diuretics (prescribed at an appropriate dosage) as initial therapy for reduction of cardiovascular or renal outcomes.1 While potentially understated, we believe that our overall conclusion that the thiazide-type diuretic was not surpassed is consistent with the data and trial objectives. SN - 0003-9926 M3 - doi: 10.1001/archinternmed.2009.372 UR - http://dx.doi.org/10.1001/archinternmed.2009.372 ER -