TY - JOUR T1 - WAlking speed is a useful marker of frailty in older persons AU - Yano Y, Inokuchi T, Kario K Y1 - 2013/02/25 N1 - 10.1001/jamainternmed.2013.1629 JO - JAMA Internal Medicine SP - 325 EP - 326 VL - 173 IS - 4 N2 - We read with great interest the report by Odden et al1 that walking speed is a marker of frailty, which could identify an increased risk of mortality in older persons with lower blood pressure (BP). Those authors showed that older persons who walked slowly might not be at risk for the adverse effects of high BP. However, for slower-walking older persons, caution is needed with regard to BP levels measured in out-of-office settings, since we recently demonstrated that slower walking speed in older hypertensive patients (n = 148; mean age, 75.5 years) was associated with high nocturnal (ie, sleep) BP or less nocturnal BP dipping (ie, nondipping), but not daytime or office BP.2 Because a high nocturnal BP level in the general population or in hypertensive patients is not only a marker of vulnerability or frailty in individuals with concurrent systematic abnormalities but also a direct contributor to the cardiovascular burden,3 it follows that a slow gait in older persons may indicate masked hypertension with poor outcomes.4 SN - 2168-6106 M3 - doi: 10.1001/jamainternmed.2013.1629 UR - http://dx.doi.org/10.1001/jamainternmed.2013.1629 ER -