TY - JOUR T1 - New statins also produce fatigue: Spontaneous reporting as a complementary system to increase safety knowledge—reply AU - Golomb BA, Koperski S Y1 - 2013/02/11 N1 - 10.1001/jamainternmed.2013.2113 JO - JAMA Internal Medicine SP - 247 EP - 248 VL - 173 IS - 3 N2 - We concur with Tarapués and colleagues. An analysis we conducted of patient reports of muscle problems (including fatigue)1 is in agreement with their Spanish data, extending fatigue adverse effects (AEs) to all statins. These data suggest that risk approximately parallels statin potency, as does our recent analysis of the US Food and Drug Administration AE reports focused on muscle-related AEs,2 although this latter analysis did not expressly address fatigue. SN - 2168-6106 M3 - doi: 10.1001/jamainternmed.2013.2113 UR - http://dx.doi.org/10.1001/jamainternmed.2013.2113 ER -