TY  - JOUR
T1  - Lactobacilli vs antibiotics to prevent recurrent urinary tract infections: An inconclusive, not inferior, outcome
AU  - Faasse M
Y1  - 2012/11/26
N1  - 10.1001/archinternmed.2012.4427
JO  - Archives of Internal Medicine
SP  - 1690
EP  - 1694
VL  - 172
IS  - 21
N2  - 
The timely report on preventive treatments for recurrent urinary tract infections (UTIs), Beerepoot et al1(p711) concluded that oral lactobacilli, when compared with trimethoprim-sulfamethoxazole, “did not meet the noninferiority criteria.”1(p711) Although this phraseology is technically correct, its meaning is somewhat opaque, and others have misunderstood the study to demonstrate that lactobacilli “were inferior to”2 or “not as effective as”3 antibiotic prophylaxis. Greater clarity may have been achieved by following the example of the Consolidated Standards of Reporting Trials (CONSORT) Group and declaring the data “inconclusive,” since the 95% confidence interval for between-treatment difference in number of symptomatic UTIs overlapped the noninferiority margin.4

SN  - 0003-9926
M3  - doi: 10.1001/archinternmed.2012.4427
UR  - http://dx.doi.org/10.1001/archinternmed.2012.4427
ER  -