TY - JOUR T1 - Will newer anticoagulants improve therapy persistence?: Comment on “persistence with therapy among patients treated with warfarin for atrial fibrillation” AU - Maxwell W, Bennett CL Y1 - 2012/11/26 N1 - 10.1001/2013.jamainternmed.616 JO - Archives of Internal Medicine SP - 1689 EP - 1690 VL - 172 IS - 21 N2 - A trial fibrillation (AF) continues to be a leading cause of cerebrovascular morbidity and mortality resulting from cardioembolic stroke. When used appropriately, oral anticoagulation therapy has been shown to decrease the incidence of cardioembolic stroke in patients with AF by 50% to 60%.1 Appropriate use of warfarin anticoagulation requires precise adherence and monitoring to optimize the risk to benefit ratio associated with therapy and to ensure that therapy can be safely continued throughout the prescribed duration. SN - 0003-9926 M3 - doi: 10.1001/2013.jamainternmed.616 UR - http://dx.doi.org/10.1001/2013.jamainternmed.616 ER -