TY  - JOUR
T1  - Zonisamide: Comment on “zonisamide for weight reduction in obese adults: a 1-year randomized controlled trial”
AU  - Katz MH
Y1  - 2012/11/12
N1  - 10.1001/2013.jamainternmed.108
JO  - Archives of Internal Medicine
SP  - 1565
EP  - 1565
VL  - 172
IS  - 20
N2  - 
Zonisamide at a daily dose of 400 mg, combined with diet and lifestyle counseling, provided moderately successful weight loss in this trial (7.3 kg [3.3 kg more than placebo] at 1 year) as it did in prior trials. The problem is that the adverse effects at this dose are substantial: 18.7% of patients experienced headache, 13.3% experienced nausea/vomiting, 9.3% experienced anxiety, and 10.7% experienced impaired memory.

SN  - 0003-9926
M3  - doi: 10.1001/2013.jamainternmed.108
UR  - http://dx.doi.org/10.1001/2013.jamainternmed.108
ER  -