TY - JOUR T1 - ADditional ways to diminish the deleterious effects of red meat—reply AU - Pan A, Willett WC, Hu FB Y1 - 2012/10/08 N1 - 10.1001/archinternmed.2012.4111 JO - Archives of Internal Medicine SP - 1424 EP - 1425 VL - 172 IS - 18 N2 - We thank Dr Gorelik and colleagues for their suggestion to use red wine to diminish the deleterious effects of red meat. Their experimental studies in rats1 and a small dietary study in 10 healthy adults2 indicated that red meat consumption promoted lipid peroxidation and increased the postprandial plasma malondialdehyde level, while the coconsumption of red wine concentrate, which is rich in polyphenols, with red meat significantly reduced the stomach oxidation process of the meat products and prevented the absorption of meat-derived aldehydes in the plasma. Although this interaction is theoretically possible, there are no data on the health effects of combining red meat with red wine or polyphenols on long-term disease outcomes. SN - 0003-9926 M3 - doi: 10.1001/archinternmed.2012.4111 UR - http://dx.doi.org/10.1001/archinternmed.2012.4111 ER -