TY  - JOUR
T1  - For human immunodeficiency virus disease, more treatment seems to be better: Comment on “immunovirologic control 24 months after interruption of antiretroviral therapy initiated close to hiv seroconversion”
AU  - Katz MH
Y1  - 2012/09/10
N1  - 10.1001/archinternmed.2012.2776
JO  - Archives of Internal Medicine
SP  - 1256
EP  - 1256
VL  - 172
IS  - 16
N2  - 
Lodi and colleagues address whether short-term combination antiretroviral therapy at the time of HIV seroconversion would enable some patients to control the virus without treatment. If early treatment enabled control in some patients, it could decrease exposure to HIV medications and, thus, the adverse effects. Unfortunately, this cohort study demonstrates that few individuals are able to control the infection without treatment. Because HIV treatment has become more effective, with fewer adverse effects, and we have gained a better appreciation of the subtle harms that HIV causes, even when the patient seems healthy, the balance is increasingly moving toward initiation of treatment at seroconversion and maintenance of treatment thereafter. In the case of antiretroviral treatment for HIV, more treatment seems to be better.

SN  - 0003-9926
M3  - doi: 10.1001/archinternmed.2012.2776
UR  - http://dx.doi.org/10.1001/archinternmed.2012.2776
ER  -