TY - JOUR T1 - THe consequences of ineffective regulation of dietary supplements AU - Marcus DM, Grollman AP Y1 - 2012/07/09 N1 - 10.1001/archinternmed.2012.2687 JO - Archives of Internal Medicine SP - 1035 EP - 1036 VL - 172 IS - 13 N2 - Under DSHEA, manufacturers of dietary supplements are not required to provide premarketing evidence of safety or efficacy or, prior to 2007, to report adverse events. After 1994, sales of supplements rose rapidly, and in 2007, consumers spent $14.8 billion out of pocket for nonvitamin, nonmineral products such as herbals.2 Increased consumption of supplements was accompanied by reports of serious adverse events and adulteration of dietary supplements by prescription drugs and heavy metals.3 SN - 0003-9926 M3 - doi: 10.1001/archinternmed.2012.2687 UR - http://dx.doi.org/10.1001/archinternmed.2012.2687 ER -